Or just put it in a pan with peppers, mushrooms, onions, garlic, etc once it hits 160°, cover with liquid (stout, beef stock, etc.), cover pan, and cook until it is fork tender to pull apart. There are recipes out there for pepper stout beef if you need more instruction. I have only ever made chuck roasts this method and for use as burnt ends. I never made one to slice like a brisket.