Way back when brisket was actually cheap... I used to use trimmed brisket flats. It was pretty good, but I can't get a good trimmed brisket flat for under $6/lb these days so I don't do that...
By the time you trim off all the fat from a packer brisket, the price per pound is going to go up toward $6 a pound I think... Now, you could potentially cut off most of the flat, trim off the rest of the fat from that flat, and then cook the remaining point and/or the thickest part of the flat as a brisket... and maybe then the pricing would be reasonable.
I personally have been buying packages of flank steak from Gordon's Food, they sell them for about $3.50/lb or something like that. I marinate a couple hunks to make steak Fajitas , and then use the rest to make Jerky with. With flank, there isn't too much fat to begin with, and if you cut it across the grain into roughly 1/2" thick strips, it actually makes some pretty darn good jerky.
But my go to for many many years is eye of round... however that sometimes is hard to find at a decent price these days. I slightly prefer the texture I get with the Flank steak, so for now I'm going with flank steak.