The most important thing on Amazon is to make sure it's Amazon themselves selling or another very reputable dealer when making large purchases. I don't seem to buy much besides groceries in a true brick and mortar retail store anymore and buy way too much from Amazon. Package weight and the shippers seem to be the biggest risk to things I buy. I ordered my Weber Summit from them originally and UPS thought it needed drug behind the truck from Chicago to Des Moines instead of hauled inside the trailer. I ordered an entertainment center that arrived in more pieces than I expected. However, I have yet to have any issues returning anything broken, damaged, or defective to Amazon. Laptops are not too big and heavy, so you should be fine. Though one thing to keep in mind, several places like Bestbuy and Target do price match Amazon now (specifically if it's Amazon.com/Amazon Services, LLC. as the seller).
I have bought monitors, laptops, projectors, etc. online without problems.